Table 1. Histoclinical characteristics of the 197 breast cancer samples.
Characteristics (N) | IBC | nIBC | p |
N = 63 (%) | N = 134 (%) | ||
Median age, years (range) (197) | 48 (24–82) | 56 (28–84) | 1.26E-03 |
Pathological tumor size, pT (133) | |||
pT1 | NA | 31 (23%) | |
pT2 | NA | 70 (53%) | |
pT3 | NA | 32 (24%) | |
Pathological axillary lymph node status, pN (133) | |||
negative | NA | 57 (43%) | |
positive | NA | 76 (57%) | |
Grade (190) | 1.35E-12 | ||
1 | 0 (0%) | 32 (24%) | |
2 | 10 (17%) | 62 (47%) | |
3 | 48 (83%) | 38 (29%) | |
IHC ER status (197) | 7.74E-03 | ||
negative | 33 (52%) | 43 (32%) | |
positive | 30 (48%) | 91 (68%) | |
IHC ERBB2 status (171) | 2.16E-04 | ||
negative | 30 (61%) | 107 (88%) | |
positive | 19 (39%) | 15 (12%) | |
IHC P53 status (163) | 5.82E-04 | ||
negative | 15 (35%) | 79 (66%) | |
positive | 28 (65%) | 41 (34%) | |
Molecular subtype (197) | 5.08E-05 | ||
basal | 13 (21%) | 25 (19%) | |
ERBB2 | 13 (21%) | 10 (7%) | |
luminal A | 9 (14%) | 63 (47%) | |
luminal B | 15 (24%) | 18 (13%) | |
normal | 13 (21%) | 18 (13%) | |
Genomic pattern (173) | 9.30E-04 | ||
complex sawtooth | 16 (33%) | 23 (19%) | |
complex firestorm | 27 (55%) | 52 (42%) | |
simplex | 6 (12%) | 49 (40%) | |
5-year MFS (191) | 37% | 80% | 4.40E-10 |
5-year OS (181) | 57% | 84% | 5.50E-11 |
NA, not assessable |