Table 5. Cox univariate and multivariate analyses of DFS in the public series of nIBCs.
Univariate Analysis | Multivariate analysis | |||||
N | HR [95%CI] | p | N | HR [95%CI] | p | |
Age, | 1372 | 0.917 [0.76–1.11] | 0.37 | |||
>50y vs ≤50y | ||||||
Pathological axillary lymph node status, | 1627 | 1.33 [1.12–1.58] | 0.0013 | 1235 | 1.25 [1.01–1.54] | 3.90E-02 |
pos vs neg | ||||||
Pathological tumor size, | 1352 | 2.08 [1.69–2.56] | 3.00E-12 | 1235 | 1.71 [1.37–2.15] | 3.00E-06 |
pT2-4 vs pT1 | ||||||
Grade, | 1291 | 2.57 [1.87–3.54] | 7.80E-09 | 1235 | 1.88 [1.33–2.65] | 3.60E-04 |
2–3 vs 1 | ||||||
IHC ER status, | 1638 | 0.571 [0.47–0.69] | 3.40E-09 | 1235 | 0.56 [0.45–0.7] | 3.00E-07 |
pos vs neg | ||||||
IHC PR status, | 453 | 0.73 [0.49–1.09] | 0.12 | |||
pos vs neg | ||||||
IBC-like vs nIBC-like | 1661 | 1.42 [1.17–1.73] | 0.00047 | 1235 | 1.34 [1.06–1.7] | 1.50E-02 |