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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Proteomics. 2010 Dec;10(23):4163–4171. doi: 10.1002/pmic.201000229

Figure 2.

Figure 2

Venn diagram illustrating the various analyses reported in Table 3. (a) We classify all sites in an organism’s coding sequences as either aggregation-prone (A) or non-aggregation-prone (N). For a subset of sites, we have structural information. We classify these sites as either buried (B) or exposed (E). (b) Analysis of codon usage by aggregation propensity for exposed sites only. (c) Analysis of codon usage by aggregation propensity for buried sites only. (d) Comparison of codon usage among exposed, aggregation-prone and buried, non-aggregation-prone sites. (e) Comparison of codon usage among buried, aggregation-prone and exposed, non-aggregation-prone sites.