Table 3.
Significantly associated haplotypes in PEPD and CD22 genes
| Gene and SNPs in the haplotype | Alleles | Haplotype | Haplotype | |||
|---|---|---|---|---|---|---|
| Frequency in cases | Frequency in controls | OR [95% CI] | P-value | |||
| PEPD | ||||||
| [CTTCA] | 0.328 | 0.367 | Reference | |||
| rs10500265 | C/G | [CTCCA] | 0.136 | 0.154 | 1.049 [0.761, 1.445] | |
| rs6510383 | C/T | [CTTCG] | 0.066 | 0.068 | 1.062 [0.687, 1.644] | |
| rs7248389 | C/T | [CCCCA] | 0.115 | 0.096 | 1.422 [0.997, 2.028] | 0.0026 |
| rs7250833 | C/T | [CTCCG] | 0.021 | 0.013 | 1.872 [0.745, 4.706] | |
| rs2241380 | A/G | [GCCTG] | 0.095 | 0.075 | 1.512 [1.020, 2.242] | |
| [CTCTG] | 0.226 | 0.188 | 1.435 [1.087, 1.894] | |||
| CD22 | ||||||
| rs756796 | A/G | [GA] | 0.105 | 0.147 | 0.716 [0.528,0.971] | |
| rs2267574 | A/T | [GT] | 0.615 | 0.623 | Reference | 0.0065 |
| [AT] | 0.280 | 0.230 | 1.253 [0.995, 1.577] | |||
The most common haplotype was used as a reference (OR of 1) and the other haplotypes were compared to that.