Table 4.
Baseline values and change on use of medical visits, hospitalizations, and decreased work productivity after 12 weeks by group.
| Resource | Non-PGB (N = 157)§ |
PGB monotherapy (N = 577)§ |
PGB add-on (N = 575)§ |
p between groups | ||||
|---|---|---|---|---|---|---|---|---|
| Number of medical visits | Baseline | Change | Baseline | Change | Baseline | Change | Baseline | Change$ |
| Total | 8.8 (7.0) | -2.4 (6.3) | 9.6 (8.1) | -4.3 (6.4) | 10.3 (7.1) | -4.3 (6.3) | 0.050 | 0.001 |
| Primary care | 5.9 (4.1) | -1.2 (4.5) | 6.7 (4.9) | -2.3 (4.6) | 7.1 (4.8) | -2.2 (4.3) | 0.011 | 0.064 |
| Pain unit | 0.5 (0.9) | 0.0 (0.8) | 0.7 (1.6) | -0.5 (1.4) | 0.6 (1.2) | -0.3 (1.1) | 0.164 | 0.003 |
| Specialist | 1.4 (1.7) | -0.5 (1.5) | 1.2 (1.5) | -0.8 (1.4) | 1.5 (1.7) | -0.8 (1.7) | 0.033 | 0.007 |
| Emergency room | 1.6 (2.8) | -0.7 (1.9) | 1.5 (3.1) | -1.0 (2.3) | 1.6 (2.4) | -1.0 (2.1) | 0.847 | 0.012 |
| Hospitalized (N, %) | 11 (7.7) | 4 (2.8) | 9 (1.8) | 1 (0.2) ╪ | 34 (6.4) | 14 (2.6) ┼ | 0.001 | 0.074 |
| Productivity | Baseline | Change | Baseline | Change | Baseline | Change | Baseline | Change |
| Days of absenteeism due to pain | 15.7 (21.7) | -5.4 (18.7) ┼ | 19.1 (23.4) | -10.4 (18.8)* | 24.4 (26.9) | -12.9 (20.4)* | 0.001 | 0.059 |
| Days working with pain | 35.0 (29.0) | -11.8 (26.6)* | 40.3 (30.2) | -23.7 (28.6)* | 43.2 (29.9) | -22.6 (28.6)* | 0.012 | 0.001 |
| Labour productivity£ | 48.1 (21.3) | +16.8 (79.7) ╪ | 46.9 (21.1) | +21.6 (24.0)* | 43.4 (21.6) | +18.7 (23.2)* | 0.007 | 0.064 |
| LWDE | 31.4 (25.9) | -14.0 (22.8)* | 35.9 (26.7) | -22.1 (23.2)* | 41.6 (28.3) | -23.1 (24.3)* | <0.001 | 0.005 |
Values expressed as means (standard deviation); LWDE: Lost -workdays equivalents; * p < 0.0001; ┼ p < 0.001; ╪ p<0.05 vs. intragroup baseline values. §Total number of analyzed patients; some patients did not report all data; $Between groups changes comparison adjusted by baseline values and number of previous drugs. £In days working with pain.