Table 1.
Cell Type | -deta/NO | +deta/NO | +deta/NO +Rp-8-pCPT-cGMPS (50μM) |
---|---|---|---|
wt-VASP | 84 ± 5 % | 56 ± 5 % # | 77 ± 7 % ≠ |
LXSN | 86 ± 3 % | 85 ±4 % | 86 ± 4 % |
S239A-VASP | 82 ± 3 % | 80 ± 6 % | 79 ± 4 % |
S239D-VASP | 64 ± 3 % * | 63 ± 5 % | 60 ± 5 % |
P ≤ 0.02 S239D-VASP vs. other cell types.
P ≤ 0.03 deta/NO-treated wt-VASP vs. wt-VASP without deta/NO.
P ≤ 0.04 deta/NO-treated wt-VASP in the presence of Rp-8-pCPT-cGMPS vs. deta/NO-treated wt-VASP without Rp-8-pCPT-cGMPS.