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. 2011 Feb 10;6(2):e16831. doi: 10.1371/journal.pone.0016831

Table 4. Quantitative methylation (%) of DNMT gene promoters: 21 serrated polyps stratified by BRAF and KRAS mutation.

Mean DNMT1 methylation (%) Mean DNMT3Amethylation (%) Mean DNMT3Bmethylation (%) Mean DNMT3Lmethylation (%)
Polyps with BRAF mutation 3.3∧ 4.3∧ 21∧ 37*
Polyps withKRAS mutation 2.8∧ 4.1∧ 27∧ 55**
Polyps WT for BRAF and KRAS 3.6 4.4 25 30

∧p-value <0.05 for DNMT1, DNMT3A and DNMT3B.

*p-value  = 0.147 (BRAF/WT).

**p-value:  = 0.0053 (KRAS/WT).