Table 2.
Case | Necrosis | Bone involved | Nesting | Glycogen | CD99 | Keratin | Des | S100 | Neuroendocrine | Molecular |
---|---|---|---|---|---|---|---|---|---|---|
1 | − | + | + | + PAS/D | + | − | − | − | − | EWS-FLI1 + RT-PCR |
2 | + | + | − | + PAS/D | + | − | − | − | + CD56 | NA |
3 | + | + | − | + PAS/D | + | f + CAM5.2 | − | − | − | NA |
4 | − | + | + | NA | + | f + AE1/3 | − | − | f + NSE | NA |
5 | + | − | + | NA | + | − | − | − | f + NSE | NA |
6 | + | + | + | + EM | + | f + AE1/3 | − | f+ | f + synaptophysin | NA |
7 | − | + | + | + PAS/D | + | − | − | − | f + synaptophysin | EWSR1 FISH + |
8 | − | + | + | − | + | − | − | − | − | EWSR1 FISH + |
9 | − | − | + | + PAS/D | + | − | − | − | f + CD56 and synaptophysin | EWSR1 FISH + |
10 | − | − | − | + PAS/D | + | − | − | f+ | f + synaptophysin | EWSR1 FISH + |
11 | − | + | + | +PASD | + | f + CAM5.2 and AE1/3 | − | NA | f + CD56 and synaptophysin | EWSR1 FISH + |
12 | − | + | + | NA | + | − | NA | NA | NA | EWSR1 FISH + |
13 | + | + | − | NA | + | − | − | − | − | EWSR1 FISH + |
14 | − | − | + | + EM | + | − | − | f+ | f + NSE | FISH equivocal |
PAS/D Periodic acid Schiff positive, diastase sensitive, EM electron microscopy, Des desmin, NSE neuron specific enolase