Figure 5.

Effects of the physical properties of the membrane on the cell-spreading dynamics. Varying the plasma membrane's biophysical properties for the same signaling input shows that its physical properties affect the spreading dynamics. (A) Rate of polymerization. (B) Fold change in radius. (C) Circularity. (D) Compliance factor for different membrane physical parameters. A change in the membrane properties results in loss of shape control during spreading for the same concentration dynamics.