TABLE 1.
Telomere length |
P for trend across quartiles3 | ||||
---|---|---|---|---|---|
Q1 (0.37–0.72 [0.65])2 | Q2 (0.72–0.83 [0.78]) | Q3 (0.83–0.96 [0.88]) | Q4 (0.95–1.75 [1.06]) | ||
Age | 65.3 ± 0.74 | 62.4 ± 0.7 | 60.6 ± 0.7 | 57.6 ± 0.7 | <0.001 |
Age-adjusted characteristics | |||||
Sex (% male) | 58.4 | 52.6 | 46.0 | 36.3 | <0.001 |
Race-ethnicity (%) | 0.58 | ||||
Whites | 11.7 | 20.2 | 23.6 | 19.2 | |
Blacks | 33.5 | 26.4 | 24.6 | 24.1 | |
Hispanics | 54.7 | 53.4 | 51.8 | 56.7 | |
Yearly gross family income (% <$25 000) | 37.6 | 42.9 | 41.3 | 39.6 | 0.89 |
Education (% ≥high school) | 76.3 | 75.1 | 70.6 | 68.4 | 0.04 |
Smoking (%current) | 11.0 | 13.3 | 11.9 | 9.9 | 0.63 |
Cigarette pack-years (n) | 9.7 ± 1.1 | 9.5 ± 1.1 | 7.2 ± 1.1 | 5.8 ± 1.1 | 0.006 |
Active leisure time (MET-min/wk) | 2495 ± 223 | 2435 ± 219 | 2422 ± 219 | 2450 ± 223 | 0.93 |
Inactive leisure time (MET-min/wk) | 1749 ± 73 | 1694 ± 72 | 1653 ± 72 | 1470 ± 73 | 0.006 |
BMI (kg/m2) | 29.0 ± 0.4 | 28.3 ± 0.4 | 29.4 ± 0.4 | 28.9 ± 0.4 | 0.55 |
Waist circumference (cm) | 100.5 ± 1.0 | 98.6 ± 0.9 | 100.3 ± 0.9 | 99.5 ± 1.0 | 0.97 |
Energy intake (kcal) | 1717 ± 55 | 1734 ± 54 | 1678 ± 54 | 1592 ± 55 | 0.11 |
Age- and energy-adjusted food group intake (servings/d) | |||||
Whole grains | 0.57 ± 0.04 | 0.55 ± 0.04 | 0.63 ± 0.04 | 0.55 ± 0.04 | 0.71 |
Refined grains | 1.34 ± 0.05 | 1.37 ± 0.05 | 1.35 ± 0.05 | 1.39 ± 0.05 | 0.62 |
Fruit | 1.85 ± 0.11 | 1.96 ±0.11 | 1.97 ± 0.11 | 1.95 ± 0.11 | 0.96 |
Vegetables | 2.41 ± 0.10 | 2.19 ± 0.09 | 2.26 ± 0.09 | 2.44 ± 0.10 | 0.47 |
Low-fat dairy | 0.73 ± 0.07 | 0.75 ± 0.07 | 0.66 ± 0.07 | 0.68 ± 0.07 | 0.94 |
High-fat dairy | 0.66 ± 0.05 | 0.64 ± 0.05 | 0.61 ± 0.05 | 0.66 ± 0.05 | 0.43 |
Seeds or nuts | 0.21 ± 0.03 | 0.28 ± 0.03 | 0.25 ± 0.03 | 0.23 ± 0.03 | 0.80 |
Nonfried fish | 0.28 ± 0.02 | 0.22 ± 0.02 | 0.21 ± 0.02 | 0.21 ± 0.02 | 0.04 |
Red meat | 0.33 ± 0.02 | 0.35 ± 0.02 | 0.35 ± 0.02 | 0.37 ± 0.02 | 0.42 |
Processed meat | 0.19 ± 0.02 | 0.13 ± 0.02 | 0.12 ± 0.02 | 0.11 ± 0.02 | 0.001 |
Fried foods | 0.22 ± 0.02 | 0.21 ± 0.02 | 0.20 ± 0.02 | 0.22 ± 0.02 | 0.68 |
Coffee | 0.97 ± 0.09 | 0.97 ± 0.09 | 1.06 ± 0.09 | 0.97 ± 0.09 | 0.95 |
Nondiet soda | 0.39 ± 0.07 | 0.41 ± 0.07 | 0.41 ± 0.07 | 0.48 ± 0.07 | 0.46 |
Age- and energy-adjusted dietary patterns (composed of summed intake of 47 weighted food groups)5 | |||||
Fats and processed meat | −0.17 ± 0.05 | −0.27 ± 0.05 | −0.24 ± 0.05 | −0.33 ± 0.05 | 0.05 |
Whole grains and fruit | 0.03 ± 0.07 | −0.06 ± 0.06 | 0.11 ±0.06 | −0.03 ± 0.07 | 0.79 |
MET, metabolic equivalent.
Telomere length (T/S ratio) range; median in brackets (all such values).
Calculated with telomere length modeled as a continuous variable.
± SE (all such values).
By design, dietary patterns derived by principal components analysis have a = 0.0 and SD = 1.0.