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Stability of FAS1-4 variants
Transition midpoints were calculated using the program KaleidaGraph by fitting curves to the data points.
| [Urea]1/2 (TUGunfolding) | [Urea]1/2 (TUGrefolding) | [Urea]50% | |
|---|---|---|---|
| m | m | m | |
| WT | 2.7 | 2.7 | 3.30 ± 0.059 |
| A546T | 1.0 | 1.1 | 2.01 ± 0.09 |
| R555Q | 2.5 | 2.5 | 3.12 ± 0.041 |
| R555W | 3.6 | 3.7 | 4.00 ± 0.056 |
