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. 2010 Dec 7;286(7):5254–5265. doi: 10.1074/jbc.M110.171884

TABLE 1.

Reactions and rates for the coarse grained model

PIP2 is phosphatidylinositol 4,5-bisphosphate.

Reactions Forward rate Backward rate Source
μm1s1 s1
Signal + cytosol.SOS ⇄ signal-SOS (membrane-bound) 0.05 0.01 Estimated
Signal + PIP2 → signal + DAG 0.05 Estimated
DAG + DGK → inactive complex + DGK 0.05 Estimated