Table 3.

Pro-X odds ratio and conditional probabilities

	p(X ∈ F), given P3						Odds ratio		ΔΔG		PPII
Peptide	F	α	Ft	Fc	αt	αc	F∗	PPII†	F∗	PPII†	Content‡
PQP	51	14	51	52	17	8	6.64	5.20	1.13	0.98	66
PDP	20	7	23	14	9	1	3.41	3.64	0.73	0.77	63
PGP	58	33	63	38	44	14	2.86	3.46	0.63	0.74	58
PAP	41	17	40	44	25	7	3.42	3.03	0.73	0.66	61
PAP′	53	29	54	51	39	14	2.74	2.61	0.60	0.57	—
PKP	39	27	48	25	36	8	1.76	2.61	0.34	0.57	59
PSP	41	19	38	50	25	10	3.01	2.50	0.66	0.55	58
PEP	34	16	32	38	23	5	2.65	2.14	0.58	0.45	61
PHP§	34	18	28	49	24	12	2.42	1.57	0.53	0.27	55
PFP	37	22	33	41	27	11	2.05	1.55	0.43	0.26	58
PCP	40	24	34	56	27	17	2.13	1.47	0.45	0.23	55
PNP	17	12	18	17	16	4	1.51	1.47	0.25	0.23	55
PRP	27	15	24	31	17	11	2.18	1.46	0.47	0.22	61
PMP	37	28	36	39	37	9	1.53	1.38	0.25	0.19	55
PLP	25	17	23	31	20	10	1.70	1.35	0.32	0.18	58
PHP¶	24	16	21	29	22	5	1.73	1.29	0.33	0.15	—
PTP	36	25	32	49	31	8	1.69	1.29	0.31	0.15	53
PWP	44	35	42	45	44	14	1.45	1.22	0.22	0.12	—
PIP	31	20	22	50	22	13	1.78	1.01	0.34	0.01	50
PVP′	28	22	23	43	27	10	1.40	1.00	0.20	0.00	—
PVP	23	19	16	41	24	6	1.29	0.75	0.15	−0.17	49
PYP	27	32	18	35	44	9	0.78	0.45	−0.14	−0.47	—

The table presents conditional probability (as a percentage) for the guest residue to be in the F region given different states of the preceding P₃ residue, along with the odds ratio and ΔΔG (in kcal/mol).

^∗Calculations based on the Zimmerman regions of the Ramachandran plot, independently of the c/t states of prolines.

^†Calculations based on both the Zimmerman regions and the c/t pattern of prolines.

^‡Reported by Rucker et al. (25) for T = 5°C based on CD experiments.

^§His is assumed to be protonated.

^¶His is assumed to be neutral.