Bifurcation analysis of a one-compartment model (N = 1) in dependence on the substrate injection Jin and the degradation parameter k2. (Shaded) Region of the occurrence of oscillations. (Solid lines) Hopf bifurcations (HB). (Shaded lines) Saddle-node bifurcations of periodic orbits (SNPO). Parameters: Jmax = 8 × 10−3, KM = 3, αmain = 3 × 10−4, n = 2, κ = 0.13, and ϕ = 0.1.