Fig. 3.
Dexamethasone inhibits ACTH release as well as ethanol-induced increases in steroid levels. Effect of dexamethasone (0.1 mg/kg, i.p.) for 90 min on the ethanol-induced increase in (a) plasma ACTH, (b) plasma progesterone, (c) 3α,5α-THP in the cerebral cortex and hippocampus and (d) adrenal StAR protein expression. Representative blot shown. StAR protein was normalized to β-actin and presented as % control. *p < 0.001 compared to control, **p < 0.01 compared to control, #p < 0.001 compared to ethanol (EtOH) (ANOVA, followed by Newman–Keuls test), n = 6 in duplicate.
