Fig. 4.
Ethanol exhibits a threshold for plasma ACTH and adrenal StAR induction, and StAR expression and plasma progesterone levels are rapidly increased. Rats were administered various doses of ethanol and (a) plasma ACTH and (b) adrenal StAR protein expression were measured. A separate group of rats was administered ethanol and blood was collected at varying time points. (c) Time course of StAR protein induction. (d) Time course of plasma progesterone induction. *p < 0.01 compared to control, #p < 0.01 compared to 1.5 g/kg ethanol, and @p < 0.05 compared to 2.5 g/ kg ethanol (Student's t-test or ANOVA followed by Newman–Keuls test where appropriate), n = 4–6 for each group in duplicate.
