Table 1. NMR Data for Sceliphrolactam (1) in DMSO-d6.
| C/H | δHa | mult (J in Hz) | δCb | |
|---|---|---|---|---|
| 1 | 173.3 | C | ||
| 2 | 4.97 | s | 94.5 | CH |
| 3 | 166.3 | C | ||
| 3-OH | 13.67 | s | ||
| 4 | 5.83 | d (15.0) | 122.2 | CH |
| 5 | 6.52 | d (15.0) | 138.6 | CH |
| 6 | 134.9 | C | ||
| 7 | 5.85 | d (11.0) | 136.4 | CH |
| 8 | 6.38 | dd (14.5, 11.0) | 129.0 | CH |
| 9 | 5.40 | dd (14.5, 7.5) | 137.1 | CH |
| 10 | 4.04 | dd (9.0, 7.5) | 70.7 | CH |
| 10-OH | 4.75 | s | ||
| 11 | 3.78 | br. d (9.0) | 75.0 | CH |
| 11-OH | 4.71 | s | ||
| 12 | 4.24 | br. s | 80.3 | CH |
| 12-OH | 4.95 | s | ||
| 13 | 201.0 | C | ||
| 14 | 6.20 | m | 121.2 | CH |
| 15 | 6.60 | dd (12.0, 11.5) | 144.3 | CH |
| 16 | 7.38 | dd (15.0, 12.0) | 126.3 | CH |
| 17 | 6.62 | d (15.0) | 147.0 | CH |
| 18 | 135.2 | C | ||
| 19 | 6.22 | m | 136.7 | CH |
| 20 | 6.20 | m | 136.4 | CH |
| 21 | 6.16 | m | 128.0 | CH |
| 22 | 5.80 | dd (15.0, 11.0) | 132.3 | CH |
| 23 | 5.45 | dd (15.0, 8.5) | 138.1 | CH |
| 24 | 2.22 | m | 40.1 | CH |
| 25a | 3.05 | m | 44.4 | CH2 |
| 25b | 2.96 | m | ||
| 25-NH | 7.70 | dd (6.5, 6.0) | ||
| 26 | 1.78 | s | 12.7 | CH3 |
| 27 | 1.58 | s | 12.7 | CH3 |
| 28 | 0.99 | d (6.5) | 16.8 | CH3 |
a
600 MHz.
b
150 MHz.