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. Author manuscript; available in PMC: 2011 Jul 13.

Published in final edited form as: Biochemistry. 2010 Jul 13;49(27):5714–5725. doi: 10.1021/bi100314n

Table 2.

Disordered regions and identity of metal ions in the metal-binding sites

					Metal binding sites

Monomer	Disordered regions	1° Bridge (H63)	2° Bridge (D 124)	D83 Orientation	Copper site (occupancy)	Zinc site (occupancy)
D124V P2₁2₁2₁
A	67–78	Broken	Broken	Flipped	Zinc (0.8)	Zinc (0.15)
	125–139
B	69–77	Broken	Broken	Flipped	Zinc (0.9)	Empty
	125–138
H80R P2₁2₁2₁
A	67–78	Broken	Intact	Wild type	Zinc (0.7)	Empty
	131–138
B	69–78	Broken	Intact	Flipped	Zinc (0.9)	Empty
	125–138
H80R P2₁
A	67–78	Broken	Intact	Flipped	Zinc (0.7)	Empty
	134–138
B	67–78	Intact	Intact	Flipped	Zinc (0.6)	Empty
	133–139
C	67–79	Intact	Intact	Flipped	Zinc (0.2)	Empty
	125–140
D	67–78	Broken	Intact	Flipped	Zinc (0.7)	Empty
	126–138