Table 4.
Cross-sectional associations of eGFR measures with hemostatic markers in MESA, 2000-2002: percent difference in hemostatic marker per 10 ml/min/1.73 m2 decrement in eGFR*
| eGFRcys, % (95% CI) | eGFRcr, % (95% CI) | |
|---|---|---|
| Soluble Thrombomodulin | 7.4 (5.9, 8.8) | 8.2 (6.3, 10.1) |
| Soluble Tissue Factor | 6.1 (3.6, 8.5) | 7.6 (4.4, 10.6) |
| D-dimer | 4.6 (3.5, 5.7) | 4.7 (3.3, 6.1) |
| Von Willebrand Factor | 2.8 (1.4, 4.2) | 2.8 (0.93, 4.6) |
| Factor VIII | 2.2 (2.7, 1.8) | 1.8 (2.5, 1.2) |
| Plasmin-Antiplasmin Complex | 2.2 (1.7, 2.7) | 3.2 (2.6, 3.8) |
| Tissue Factor Pathway Inhibitor | 2.1 (1.2, 3.1) | 1.4 (0.2, 2.6)‡ |
| Plasminogen Activator Inhibitor-1 | 4.7 (2.0, 7.4) | 1.3 (-2.3, 5.1)§ |
| Fibrinogen | 1.0 (0.74, 1.2) | 1.0 (0.64,1.3) |
*Note: Models adjusted for age, race, gender, SES (income), site, current smoking, current alcohol, BMI, prevalent DM, prevalent HTN, statin use, ACE-I, LDL, HDL, TG, fasting glucose, and ln(albumin/creatinine). All p values are <0.001 unless otherwise noted.
‡p < 0.05
§Non-significant