Table 9.
Supplement intake by APOE4 genotype in females in the Personalized Medicine Research Project
| With E4 | No E4 | ||||||||
| Nutrient | N* | Mean | S.D. | Median | N* | Mean | S.D. | Median | Wilcoxon p-value |
| Supp. Vitamin A (IU) | 1750 | 2965.2 | 2801.5 | 3571.4 | 5071 | 2789.8 | 2845.7 | 3571.4 | 0.006 |
| Supp. Vitamin A (mcg RAE) | 1750 | 889.6 | 840.4 | 1071.4 | 5071 | 836.9 | 853.7 | 1071.4 | 0.006 |
| Supp. Beta Carotene | 1750 | 350.6 | 329.0 | 428.6 | 5071 | 325.1 | 323.0 | 428.6 | 0.002 |
| Supp. Vitamin E | 1750 | 52.6 | 113.6 | 20.1 | 5071 | 50.8 | 108.8 | 20.1 | 0.046 |
| Supp. Vitamin C | 1750 | 140.5 | 273.5 | 60.0 | 5071 | 134.4 | 262.3 | 60.0 | 0.076 |
| Supp. Thiamin (mg) | 1750 | 1.4 | 2.0 | 1.5 | 5071 | 1.3 | 1.9 | 1.1 | 0.002 |
| Supp. Riboflavin (mg) | 1750 | 1.3 | 1.5 | 1.7 | 5071 | 1.2 | 1.5 | 1.2 | 0.002 |
| Supp. Niacin (mg) | 1750 | 13.7 | 13.4 | 20.0 | 5071 | 12.7 | 12.9 | 14.3 | 0.003 |
| Supp. Vitamin B6 (mg) | 1750 | 4.4 | 10.6 | 2.0 | 5071 | 4.3 | 10.8 | 1.4 | 0.014 |
| Supp. Folic Acid (mcg) | 1750 | 230.2 | 191.8 | 285.7 | 5071 | 215.8 | 194.8 | 285.7 | 0.004 |
| Supp. Vitamin B12 (mcg) | 1750 | 3.3 | 2.8 | 4.3 | 5071 | 3.1 | 2.8 | 4.3 | 0.002 |
| Supp. Vitamin D (mcg) | 1750 | 286.6 | 365.6 | 16.6 | 5071 | 290.5 | 371.6 | 16.6 | 0.866 |
| Supp. Calcium (mg) | 1750 | 50.8 | 47.3 | 71.4 | 5071 | 47.1 | 47.2 | 28.6 | 0.003 |
| Supp. Magnesium (mg) | 1750 | 10.4 | 10.3 | 12.9 | 5071 | 9.9 | 10.2 | 12.9 | 0.111 |
| Supp. Iron (mg) | 1750 | 8.4 | 8.2 | 10.7 | 5071 | 7.9 | 8.3 | 4.3 | 0.007 |
| Supp. Zinc (mg) | 1750 | 1.0 | 0.9 | 1.4 | 5071 | 0.9 | 0.9 | 0.6 | 0.003 |
| Supp. Copper (mg) | 1750 | 221.4 | 186.7 | 285.7 | 5071 | 205.9 | 188.0 | 285.7 | 0.002 |
| Supp. Selenium (mcg) | 1750 | 0.6 | 4.9 | 0.0 | 5071 | 0.7 | 5.4 | 0.0 | 0.375 |
| Supplement Users Only | |||||||||
| Supp. Vitamin A (IU) | 1208 | 4295.6 | 2377.5 | 5000.0 | 3295 | 4293.5 | 2450.7 | 5000.0 | 0.931 |
| Supp. Vitamin A (mcg RAE) | 1208 | 1288.7 | 713.3 | 1500.0 | 3295 | 1288.0 | 735.2 | 1500.0 | 0.931 |
| Supp. Beta Carotene | 1201 | 510.9 | 275.4 | 600.0 | 3268 | 504.4 | 267.2 | 600.0 | 0.558 |
| Supp. Vitamin E | 1261 | 73.1 | 128.1 | 20.1 | 3465 | 74.3 | 124.8 | 20.1 | 0.468 |
| Supp. Vitamin C | 1314 | 187.2 | 301.5 | 60.0 | 3612 | 188.6 | 293.9 | 60.0 | 0.262 |
| Supp. Thiamin (mg) | 1228 | 2.0 | 2.1 | 1.5 | 3323 | 1.9 | 2.1 | 1.5 | 0.841 |
| Supp. Riboflavin (mg) | 1228 | 1.9 | 1.5 | 1.7 | 3323 | 1.8 | 1.4 | 1.7 | 0.841 |
| Supp. Niacin (mg) | 1231 | 19.5 | 11.8 | 20.0 | 3346 | 19.2 | 11.3 | 20.0 | 0.857 |
| Supp. Vitamin B6 (mg) | 1234 | 6.2 | 12.2 | 2.0 | 3366 | 6.5 | 12.7 | 2.0 | 0.634 |
| Supp. Vitamin B12 (mcg) | 1220 | 330.2 | 140.6 | 400.0 | 3310 | 330.6 | 142.0 | 400.0 | 0.954 |
| Supp. Folic Acid (mcg) | 1195 | 4.9 | 2.0 | 6.0 | 3238 | 4.8 | 2.0 | 6.0 | 0.697 |
| Supp. Vitamin D (mcg) | 941 | 533.0 | 342.5 | 500.0 | 2727 | 540.2 | 349.1 | 500.0 | 0.686 |
| Supp. Calcium (mg) | 1086 | 81.9 | 32.5 | 100.0 | 2936 | 81.4 | 32.5 | 100.0 | 0.681 |
| Supp. Magnesium (mg) | 1110 | 16.4 | 8.2 | 18.0 | 3059 | 16.5 | 8.0 | 18.0 | 0.290 |
| Supp. Iron (mg) | 1107 | 13.2 | 6.5 | 15.0 | 2998 | 13.3 | 6.6 | 15.0 | 0.908 |
| Supp. Zinc (mg) | 1086 | 1.6 | 0.6 | 2.0 | 2936 | 1.6 | 0.7 | 2.0 | 0.681 |
| Supp. Copper (mg) | 1195 | 324.2 | 133.1 | 400.0 | 3238 | 322.5 | 133.1 | 400.0 | 0.697 |
| Supp. Selenium (mcg) | 23 | 42.9 | 0.0 | 42.9 | 82 | 42.9 | 0.0 | 42.9 | 1.000 |
*N refers to the number of participants