Table 3.

Kinetic constants of the tet operon reaction network.

kinetic constant	Ref.	kinetic constant	Ref.	kinetic constant	Ref.	kinetic constant	Ref.
k1 = 10+9	[31]h	k18 = 5.80·10-3	[31]	k35 = 30	[44]	k52 = 10+5	e
k2 = 10	[31]h	k19 = 0.10	[20]	k36 = 30	[44]a	k53 = 100	[44]
k3 = 10+8	[31]h	k20 = 4.80·10+5	[20]	k37 = 621	[8]b	k54 = 100	[44]a
k4 = 10-4	[31]h	k21 = 10-4	[20]	k38 = 7.23·10+6	[40,63]h	k55 = 394	[64]b
k5 = 5.00·10+8	[16,31]h	k22 = 2.40·10+5	[20]	k39 = 0.10	[63]h	k56 = 3.85·10-5	f
k6 = 10-4	[31]h	k23 = 2.00·10-4	[20]	k40 = 0.013	[63]	k57 = 3.85·10-5	f
k7 = 30	[31]h	k24 = 5.80·10-3	[31]	k41 = 30	[44]	k58 = 0.002	e
k8 = 0.10	[31]h	k25 = 0.10	[20]	k42 = 10+5	e	k59 = 0.002	e
k9 = 3.30·10-4	[65]	k26 = 4.8·10+4	[40,63]h	k43 = 100	[44]	k60 = 2.67·10-6	[43]
k10 = 4.80·10+5	[20]	k27 = 0.10	[63]h	k44 = 100	[44]a	k61 = 1	[13]c
k11 = 10-4	[20]	k28 = 0.013	[63]	k45 = 207	[8]b	k62 = 4.90·10-5	[21]d
k12 = 2.40·10+5	[20]	k29 = 30	[44]	k46 = 8.60·10+6	[19,63]h	k63 = 10+8	g
k13 = 2.00·10-4	[20]	k30 = 30	[44]a	k47 = 0.10	[63]h	k64 = 10+8	[31]
k14 = 4.80·10+5	[20]	k31 = 621	[8]b	k48 = 0.013	[63]	k65 = 5.00·10+8	[16,31]
k15 = 10-4	[20]	k32 = 9.10·10+5	[40,63]h	k49 = 30	[44]	k66 = 0.10	[20]
k16 = 2.40·10+5	[20]	k33 = 0.10	[63]h	k50 = 30	[44]a	k67 = 0.10	[20]
k17 = 2.00·10-4	[20]	k34 = 0.013	[63]	k51 = 1182	[64]b

Units on k: first order reactions: sec^-1, second order reactions: M^-1sec^-1, third order reactions: M^-2sec^-1, fourth order reactions: M^-3sec^-1, fifth order reactions: M^-4sec^-1.

^a Scale parameter of the gamma distributed event (sec).

^b Shape parameter of the gamma distributed event.

^c k_cat of Michaelis Menten kinetics.

^d K_M of Michaelis Menten kinetics.

^e Rate adjusted to give 20 protein molecules per mRNA transcript.

^f Rate adjusted for 5 hours half life.

^g Rate adjusted for very fast reaction.

^h Rate calculated through equilibrium constant by assuming the forward and calculating the reverse rate.