Table 5. AUC for Incident CVD by Imaging Measures of Subclinical Disease.
Measure | Overall (n=4965) |
Men (n=2365) |
Women (n=2600) |
---|---|---|---|
CHD (n=187) | |||
Base model* | 0.766 | 0.714 | 0.805 |
Base model+CAC | 0.815† | 0.785† | 0.835‡ |
Base model+carotid IMT | 0.777‡ | 0.720 | 0.820 |
Base model+LV mass | 0.768 | 0.722 | 0.805 |
Base model+LV mass/volume | 0.772‡ | 0.725 | 0.809 |
Base model+CAC+IMT+LV mass | 0.817† | 0.787† | 0.837 |
Stroke (n=65) | |||
Base model | 0.835 | 0.834 | 0.858 |
Base model+CAC | 0.836 | 0.838 | 0.857 |
Base model+carotid IMT | 0.835 | 0.833 | 0.856 |
Base model+LV mass | 0.843 | 0.839 | 0.869 |
Base model+LV mass/volume | 0.843 | 0.841 | 0.864 |
Base model+CAC+IMT+LV mass | 0.844 | 0.840 | 0.867 |
Heart failure (n=91) | |||
Base model | 0.818 | 0.790 | 0.851 |
Base model+CAC | 0.826 | 0.794 | 0.862 |
Base model+carotid IMT | 0.818 | 0.791 | 0.851 |
Base model+LV mass | 0.853‡ | 0.845§ | 0.868 |
Base model+LV mass/volume | 0.818 | 0.790 | 0.858 |
Base model+CAC+IMT+LV mass | 0.856‡ | 0.849§ | 0.881 |
All CVD (n=297) | |||
Base model | 0.773 | 0.738 | 0.806 |
Base model+CAC | 0.797‖ | 0.777§ | 0.819 |
Base model+carotid IMT | 0.775 | 0.739 | 0.810 |
Base model+LV mass | 0.785‡ | 0.757‡ | 0.811 |
Base model+LV mass/volume | 0.777 | 0.745 | 0.806 |
Base model+CAC+IMT+LV mass | 0.806† | 0.790† | 0.824‡ |
P values stand for comparison with the respective base model. CAC score refers to the natural logarithm of (CAC+1) values. Carotid IMT refers to a composite z score for overall maximal IMT. LV mass was adjusted for body size when implied as a separate imaging measure but not in LV mass/volume ratio. Boldface indicates to imaging measures leading to the highest increment in AUC when added to the base model.
Consists of traditional risk factors only.
P≤0.0001.
P<0.05.
P<0.01.
P<0.001.