Table 2.
Distribution of 39 genotype-I PRRSV isolates according to their cytokine profiles.
| BMDC | SwC3+ | |||||||
|---|---|---|---|---|---|---|---|---|
| IL-10 pg/mL* | NA | NA | 183 ± 137 (280-86) | 410 ± 98 (522-297) | NA | NA | 323 ± 259 (752-119) | 501 ± 363 (1352-77) |
| TNF-α Pg/mL* | NA | 502 ± 293 (1070-91) | NA | 432 ± 300 (941-201) | NA | 879 ± 715 (2,039-103) | NA | 1321 ± 939 (2847-229) |
| Total strains | 13 | 19 | 2 | 5 | 5 | 13 | 4 | 17 |
*Cytokine-inducing profiles for IL-10 and TNF-α were obtained using bone marrow-derived dendritic cells and sorted SwC3+ peripheral blood mononuclear cells inoculated at a multiplicity of infection of 0.01. Values in the table show the average, standard deviation and range (pg/mL) of the concentrations in cell culture supernatants obtained for a set of strains inducing a given cytokine.