Table 2.
Genes with most significantly altered transcript levels
| Gene ID a | Annotation b | log2 FC c | q d |
|---|---|---|---|
| 15 most significantly increased | |||
| FGSG_04092 | probable cytochrome P450 51 (eburicol 14 alpha-demethylase) | 7.35 | 0.006 |
| FGSG_02255 | conserved hypothetical protein | 6.57 | 0.006 |
| FGSG_02748 | related to endothelin-converting enzyme 1 | 2.80 | 0.012 |
| FGSG_09764 | related to phosphomevalonate kinase | 3.33 | 0.012 |
| FGSG_03686 | probable cytochrome P450 (involved in C-22 denaturation of the ergosterol side-chain) | 3.69 | 0.012 |
| FGSG_04492 | conserved hypothetical protein | 4.61 | 0.012 |
| FGSG_10490 | conserved hypothetical protein | 3.46 | 0.012 |
| FGSG_10170 | conserved hypothetical protein | 1.80 | 0.012 |
| FGSG_02721 | conserved hypothetical protein | 1.45 | 0.012 |
| FGSG_13888 | related to emopamil-binding protein | 7.35 | 0.012 |
| FGSG_03489 | conserved hypothetical protein | 4.35 | 0.012 |
| FGSG_04874 | conserved hypothetical protein | 6.78 | 0.012 |
| FGSG_05739 | conserved hypothetical protein | 6.94 | 0.013 |
| FGSG_04034 | conserved hypothetical protein | 3.97 | 0.013 |
| FGSG_02771 | probable KES1 - involved in ergosterol biosynthesis | 3.05 | 0.013 |
| 15 most significantly decreased | |||
| FGSG_02499 | related to amino acid transport protein | -1.49 | 0.012 |
| FGSG_06437 | related to triacylglycerol lipase V precursor | -2.18 | 0.012 |
| FGSG_13414 | conserved hypothetical protein | -2.13 | 0.012 |
| FGSG_00788 | conserved hypothetical protein | -2.12 | 0.016 |
| FGSG_10119 | related to threonine dehydratase | -2.06 | 0.027 |
| FGSG_02349 | probable tyrosine-tRNA ligase | -2.33 | 0.029 |
| FGSG_02950 | related to neutral amino acid permease | -2.20 | 0.029 |
| FGSG_09392 | conserved hypothetical protein | -1.04 | 0.029 |
| FGSG_09354 | probable neutral amino acid permease | -2.16 | 0.029 |
| FGSG_04215 | related to monocarboxylate transporter 2 | -3.20 | 0.032 |
| FGSG_00296 | probable ILV1 - anabolic serine and threonine dehydratase precursor | -1.94 | 0.033 |
| FGSG_10809 | conserved hypothetical protein | -1.75 | 0.033 |
| FGSG_08394 | conserved hypothetical protein | -1.38 | 0.033 |
| FGSG_10626 | related to phenazine biosynthesis protein phz | -2.16 | 0.033 |
| FGSG_09647 | probable histidinol-phosphate transaminase | -2.17 | 0.033 |
a The given gene ID is the entry number of the F. graminearum genome annotation FG3. b Annotation as provided by the MIPS Fusarium graminearum genome database (FGDB). c The relative transcriptional differences between fungicide-treatment vs. untreated control given as log2 transformed fold-changes. d Statistical assessment of transcriptional differences by ODP. The q value is a measure of the false-positive discovery rate in a given set of genes.