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. 2011 Jan 1;3(1):67–75. doi: 10.4161/mabs.3.1.14021

Table 4B.

Single dose pharmacokinetic parameters of CMAB009: two-compartmental analysis

Parameters (units) CMAB009 dose (mg/m2)
100 250 400
Ke (h−1) 0.009 ± 0.002 0.009 ± 0.001 0.008 ± 0.001
Tl/2ke (h) 77.15 ± 13.96 79.79 ± 6.91 86.25 ± 9.93
AUC (µg.h/mL) 2571.76 ± 626.07 13124.59 ± 3701.87 23666.02 ± 3268.71
C//F (mL/h.m2) 40.65 ± 10.92 20.28 ± 7.71 17.16 ± 2.23
VSS (mL/ m2) 2749.034 ± 363.56 2097.22 ± 518.63 2176.37 ± 627.10