Table 4B.
Parameters (units) | CMAB009 dose (mg/m2) | ||
100 | 250 | 400 | |
Ke (h−1) | 0.009 ± 0.002 | 0.009 ± 0.001 | 0.008 ± 0.001 |
Tl/2ke (h) | 77.15 ± 13.96 | 79.79 ± 6.91 | 86.25 ± 9.93 |
AUC (µg.h/mL) | 2571.76 ± 626.07 | 13124.59 ± 3701.87 | 23666.02 ± 3268.71 |
C//F (mL/h.m2) | 40.65 ± 10.92 | 20.28 ± 7.71 | 17.16 ± 2.23 |
VSS (mL/ m2) | 2749.034 ± 363.56 | 2097.22 ± 518.63 | 2176.37 ± 627.10 |