Table 5A.

Multiple dose pharmacokinetic parameters of CMAB009: non-compartmental analysis

Group	Patient no.	Kτ4	t1/2 τ4 (h)	AUC (µg.h/mL)
Group A	1	0.0002	117.5	8195
	3	0.009	73.7	12491.4
	4	0.01	66.6	14695.1
	5	0.007	97.6	10235.8
	6	0.005	144.4	17344.8
	7	0.005	154	18525.7
	8	0.008	92.4	16665.3
	Mean	0.007	106.6	14021.9
	SD	0.002	33.5	3860
Group B	9	0.006	111.8	20437.3
	10	0.007	100.4	13282.8
	12	0.006	126	19749.6
	13	0.007	93.6	15195.2
	15	0.007	101.9	18265.3
	16	0.008	86.6	16779.3
	17	0.005	130.8	18685.3
	18	0.006	115.5	13372.5
	Mean	0.007	108.3	16970.9
	SD	0.0009	15.5	2779.8