Table 1.

Number of neurons in young adult dt/dt mice compared with those in age-matched wild-type mice

	Region	Neuronal number
		wild-type	dt/dt
Types of neuron	Lumbar sympathetic ganglia	2147 ± 131	736 ± 362*
	Ciliary ganglia	187 ± 9	80 ± 29*

The neuronal numbers of ganglia were calculated from wild-type (n = 5) and dt/dt (n = 4) mice. Neurons with both the nucleus and nucleolus in the focal plane were counted. Results are expressed as mean ± SD and *indicates a value statistically different (t-test, P < 0.01) from the wild-type control. The neuronal number in sympathetic ganglia and parasympathetic ciliary ganglia of dt/dt is significantly reduced compared with those of wild-type mice.