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. 2011 Jan 28;10:10. doi: 10.1186/1476-4598-10-10

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Copyright ©2011 Guo et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Kaplan-Meier curves of overall survival stratified by Bmi-1 status according TNM classification. (A, B) In each panel of patients with different tumor size, the overall survival was significantly shorter in the high Bmi-1 expression group than in the other group. (C, D) No obvious difference was seen according to the Bmi-1 expression in the N0 (C, P = 0.061) and N1+2+3 (D, P = 0.248) patients subgroups. (E, F) In the M0 panel and clinical stage II+III+IV panel, the overall survival was significantly shorter in patients with high Bmi-1 expression compared to those with low expression (E, *P = 0.018; F, P = **0.009).