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. Author manuscript; available in PMC: 2012 Feb 28.
Published in final edited form as: Brain Res. 2010 Dec 20;1376:88–93. doi: 10.1016/j.brainres.2010.12.052

Figure 2.

Figure 2

Influence of calcitonin gene related peptide (CGRP) (10−8, 10−6 M) on pial artery diameter before injury (control), 2.5h after hypoxia/ischemia (H/I), 2.5h after H/I treated with tPA (2 mg/kg iv), 2.5h after H/I treated with EEIIMR (1 mg/kg iv), 2.5h after H/I treated with EEIIMD (1 mg/kg iv), and 2.5h after H/I treated with U 0126 (1 mg/kg iv), n=5. A: pre-treatment 30 min prior to H/I, B: post-treatment 2h after H/I. Baseline pial artery diameters were 140 ± 16, 121 ± 11, 117 ± 10, 123 ± 13, and 121 ± 12 μm for control, H/I, H/I + tPA, H/I + EEIIMR, H/I + EEIIMD, and H/I + U 0126 pretreated respectively. Mean arterial blood pressure was 72 ± 9, 66 ± 7, 65 ± 7, 66 ± 8 and 68 ± 9 mm Hg, respectively, under the same sequence of experimental groups. *p<0.05 compared with corresponding control value +p<0.05 compared with corresponding H/I non-treated value.