Fig. 8.
Tibial nerve endoneurial microvessels in EAN resulting from injection of P2-sensitized T cell lines or T cells from rats with adjuvant arthritis. Vessel from control rat injected with T cells sensitized to adjuvant arthritis (a) or from a rat where EAN was induced by injection of P2-sensitized T cells (b) and (c). Upper inset in a is from control rat and lower inset from a rat with EAN. Arrows indicate interendothelial clefts, which have tight junctions in (a) and are open in (c). Note fragmented endothelial basal lamina in (c) below arrow. Bar 100 μm in insets, 1.43 μm in (a), 2.00 μm in (b) and (c). Reproduced with permission [131]