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. Author manuscript; available in PMC: 2011 Feb 13.
Published in final edited form as: Dev Biol. 2008 Sep 24;324(1):131–138. doi: 10.1016/j.ydbio.2008.09.012

Figure 6. Model for independent function of N1 and C1 in heart induction.

Figure 6

C1 acts indirectly by inhibiting Wnt signaling in the endoderm stimulate the production of a diffusible intermediary that initiates cardiogenesis in mesoderm (Foley and Mercola, 2005). N1 might act on endoderm or directly on cardiogenic mesoderm (see text).