Table 2.

Relative efficiencies for estimates under a gene-environment interaction model, logit(Pr(D = 1∣G,E)) = β₀ + β₁G + β₂E + β₃G × E.

Design	ORG = 1.5	ORE = 2	ORG×E = 3
	p = 0.1, β0 = -3
CC-Family	0.521	0.484	0.706
AF-Family	0.462	0.469	0.525
HR-Family	0.670	0.788	1.076
Combined	0.686	0.614	0.905
	p = 0.1, β0 = -2
CC-Family	0.832	0.810	0.884
AF-Family	0.711	0.623	0.780
HR-Family	0.934	1.070	1.090
Combined	1.000	0.917	1.011
	ORG = 10	ORE = 2	ORG×E = 15
	p = 0.01, β0 = -3
CC-Family	1.467	0.507	1.809
AF-Family	1.551	0.323	2.628
HR-Family	1.487	0.884	2.619
Combined	1.731	0.663	2.478