TABLE 3.

OPTIMIZED VALUES OBTAINED BY APPLYING CONSTRAINTS ON VARIABLES AND RESPONSE

Variables	Quantity (ml)	Expected particle size*	Observed Particle size*
A-Labrafil 2609WL	0.16
B-Labrasol	0.17	24.87	28.33
C-Cremophor EL	0.22

A-Labrafil 2609WL, B-Labrasol, C-Cremophor EL

^*particle size in nm.