TABLE 3.
Parameters | IE1C3 | IE2C4 | ||||
---|---|---|---|---|---|---|
Without surfactant | Tween 80 (1% v/v) | SLS (0.5% w/v) | Without surfactant | Tween 80 (1% v/v) | SLS (0.5% w/v) | |
ra | 0.9685 | 0.9923 | 0.9933 | 0.9891 | 0.9802 | 0.9711 |
Kb | 0.0119 | 0.0174 | 0.0224 | 0.0192 | 0.0127 | 0.0157 |
nc | 1.50 | 1.42 | 1.31 | 1.38 | 1.32 | 1.41 |
t10%d | 3.1 | 3.4 | 2.9 | 3.3 | 3.7 | 3.0 |
t50%e | 10.5 | 10.6 | 9.4 | 10.5 | 11.1 | 7.8 |
t90%f | 15.3 | 16.1 | 14.4 | 16.1 | 17.1 | 14.7 |
Correlation coefficient.
Release rate constant.
Diffusional exponent indicative of the release mechanism.
Time for 10% of the drug release (in h).
Time for 50% of the drug release (in h).
Time for 90% of the drug release (in h).