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. 2011 Jan;7(1 Suppl 1):4–16.

Table 3.

Efficacy Outcomes with Peginterferon (PEG) and Ribavirin (RBV) with or without Boceprevir (BOC) in the SPRINT-2 Trial

Outcome Nonblack patients Black patients
BOC (RGT) + PEG/RBV (n=316) BOC (44 weeks) + PEG/RBV (n=311) PEG/RBV (n=311) BOC (RGT) + PEG/RBV (n=52) BOC (44 weeks) + PEG/RBV (n=55) PEG/RBV (n=52)
SVR, %
  • Overall

67 68 40 42 53 23
  • Patients with Week 4 HCV RNA decline <1 log10 IU/mL, %

29 39 5 25 31 0
  • Patients with Week 4 HCV RNA decline ≥1 log10 IU/mL, %

82 82 52 67 61 46
Relapse, % 9 5 23 12 17 14
HCV

hepatitis C virus

RGT

response-guided therapy

SVR

sustained virologic response.