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Ex vivo imaging of Au nanoshells dispersed in human breast carcinoma using PT-OCT.[90] a–c) Phase-sensitive PT-OCT signals superimposed onto structural (B-mode) OCT images of tissue impregnated with nanoshells. Photothermal modulation was performed at various frequencies, with optimal contrast obtained at 5 KHz. d,e) Real-time phase modulation and corresponding power spectra, measured at position ‘×’ in c). Published with permission from the Optical Society of America.
