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Brain regions showing reduced CMRglc on FDG-PET in cognitively normal individuals with a maternal family history of AD (FHm) as compared to demographically matched subjects with a paternal family history (FHp) and with a negative family history of AD (FH-) [57]. Statistical parametric maps showing regions of hypometabolism in NL FHm are displayed on a purple-to-yellow color coded scale at P<0.001. Figure shows the left lateral and superior views of a 3D volume-rendered MRI.
