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. Author manuscript; available in PMC: 2011 Feb 14.
Published in final edited form as: Diagn Mol Pathol. 2008 Sep;17(3):145–150. doi: 10.1097/PDM.0b013e31815aca19

FIGURE 2.

FIGURE 2

Immunohistochemical correlates of uterine smooth muscle tumors and their pulmonary counterparts. Panel A shows a typical result for the HHF-35 immunohistochemical test for the pulmonary lesions of the benign metastasizing leiomyomas; the strong signal documents the smooth muscle origin of the lesion. Each of the benign metastasizing leiomyomas was negative for the p53 antigen (panel B). In contrast, note the nuclear-based signal, typical of most of the leiomyosarcomas (panel C, arrow). Panel D shows the strong signal for bcl-2, noted in the pulmonary lesion of the benign metastasizing leiomyoma, which is indicative of its uterine origin.