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. 2010 Dec 21;40(2):274–277. doi: 10.1093/ageing/afq158

Table 2.

Prevalence of prescribing problems at hospital discharge and their relationship with Type A ADRs in the subsequent 12 months (n = 359)

Prescribing problems n Per cent Unadjusted odds ratio (95% CI) Adjusted odd ratio (95% CI)a
Any dosage problem 148 41.2 0.89 (0.57–1.39) 0.72 (0.44–1.17)
Incorrect directions 159 44.3 0.85 (0.548–1.33) 0.72 (0.44–1.16)
Any drug–drug interaction 21 5.9 2.70 (1.11–6.55) 2.37 (0.91–6.11)
Any drug–disease interaction 48 13.4 2.09 (1.14–3.85) 1.93 (1.00–3.72)

aControlling for basic activities of daily living score and self-rated health. Neither the number of high-risk medications nor the comorbidity index were retained in the backward selection (alpha = 0.15) multivariable logistic regression model. Hosmer–Lemeshow goodness-of-fit test (χ2 = 7.05; df = 8; P = 0.53) suggests adequate model fit. No collinearity problems were detected with the final multivariable model.