Table 1.
Cargo proteins in clathrin-independent endocytosis
| Cargo* | Function | Refs |
|---|---|---|
| MHC class I molecule | Immune responses | 14 |
| MHC class II molecule (peptide-loaded) | Immune responses | 22 |
| CD1a | Immune responses | 19 |
| β-integrins | Cell–extracellular matrix interactions and adhesion | 15, 16 |
| E-cadherin | Cell–cell junctions | 91 |
| PMP22§ | Myelination | 123 |
| CD44 (hyaluronan receptor) | Cell–extracellular matrix interactions | 18 |
| CD98 (SLC3A2 and 4F2HC) | Interacts with β-integrins, ICAM1 and the heavy chain of amino acid transporters | 18 |
| CD147 (EMMPRIN and basigin) | Cell–extracellular matrix interactions | 18 |
| ICAM1 (CD54) | Cell–extracellular matrix interactions and adhesion | 23 |
| Syndecan 1 | Cell–extracellular matrix interactions | 21 |
| CD55 (DAF) | GPI-AP; protects cell from complement | 57 |
| CD59 (protectin) | GPI-AP; protects cell from complement | 17 |
| Mucolipin 2§ | TRP-like cation channel | 57 |
| Kir3.4 (GIRK4 and KCNJ5) | Inwardly rectifying potassium channel | 23 |
| GLUT1 (SLC2A1) | Glucose transporter | 18 |
| LAT1 (SLC7A5) | L-type amino acid transporter | 18 |
| β2 adrenergic receptor§ (no ligand) | Signalling receptor | 20 |
| M3 receptor§ (no ligand) | Signalling receptor | 20 |
| MGLUR7§ (no ligand) | Signalling receptor | 124 |