Figure 10.

Effects of flurazepam and gabaxadol on motor incoordination in Gad2 (−/−) and wild-type mice on the 129N2 background. (a, b) Recovery from motor incoordination measured by time on rotarod before and after flurazepam at 35 g/kg (a) and 15 mg/kg (b) (n = 6–8 per genotype). (c, d) Recovery from motor incoordination measured by time on rotarod before and after gabaxadol at 10 g/kg (c) and 5 mg/kg (d). *P < 0.05; **P < 0.01; ***P < 0.001—significant difference relative to wild-type mice for same concentration of drug (Bonferroni post-test) (n = 8 per genotype).Values represent mean ± standard error of the mean