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. Author manuscript; available in PMC: 2012 Feb 20.
Published in final edited form as: Virology. 2010 Dec 14;410(2):283–290. doi: 10.1016/j.virol.2010.11.010

Figure 3. VEGF, but not IL-8, is required for the increased migration of HMVECs in vitro.

Figure 3

Conditioned media from HFKs retrovirally transduced with LXSN and HPV 16E6E7 depleted of (A) IL-8 or (B) VEGF were (C) tested for the ability to induce migration of endothelial cells as in Figure 2. The results (mean number of migrated cells per high power field (HPF) ± SEM) are representative of three experiments each conducted in triplicate. p< 0.0001 for LXSN vs HPV 16E6E7 (control isotype IgG2B); p< 0.002 for LXSN vs HPV 16E6E7 (depleted IL-8) and LXSN vs HPV 16E6E7 (control isotype IgG1).