Table 3.
Associations between RPS6KA2 and rectal cancer
| Rectal |
|||||
|---|---|---|---|---|---|
| Controls | Cases | Cases | |||
| N | N | OR1 | (95% CI) | ||
| RPS6KA2 rs10946164(C>T) | |||||
| CC | 312 | 292 | 1.00 | ||
| CT/TT | 647 | 462 | 0.78 | (0.63, 0.95) | |
| P max | 0.02 | ||||
| RPS6KA2 rs9347128(C>G) | |||||
| CC/CG | 791 | 585 | 1.00 | ||
| GG | 168 | 169 | 1.34 | (1.05, 1.71) | |
| P max | 0.03 | ||||
| RPS6KA2 rs9295361(C>A) | |||||
| CC/CA | 920 | 710 | 1.00 | ||
| AA | 39 | 44 | 2.00 | (1.24, 3.23) | |
| p max | 0.21 | ||||
| RPS6KA2 rs6911624(G>A) | |||||
| GG | 614 | 530 | 1.00 | ||
| GA | 308 | 206 | 0.77 | (0.62, 0.95) | |
| AA | 37 | 18 | 0.58 | (0.32, 1.04) | |
| p max | 0.01 | ||||
| RPS6KA2 rs2345067(T>C) | |||||
| TT | 267 | 235 | 1.00 | ||
| TC | 463 | 358 | 0.85 | (0.68, 1.06) | |
| CC | 229 | 161 | 0.73 | (0.56, 0.97) | |
| p max | 0.22 | ||||
| RPS6KA2 rs2072638(T>C) | |||||
| TT/TC | 872 | 643 | 1.00 | ||
| CC | 79 | 102 | 1.79 | (1.31, 2.45) | |
| p max | <0.01 | ||||
| RPS6KA2 rs7745781(A>G) | |||||
| AA | 730 | 520 | 1.00 | ||
| AG/GG | 229 | 234 | 1.40 | (1.13, 1.74) | |
1
Adjusted for age, center, race/ethnicity, and sex.