Table 2.
Affinity constants for the interaction between [Au(CQ)(PPh3)]PF6 and calf thymus DNA
Compounds | Absorption Titration | Emission Titration | ||
---|---|---|---|---|
Kb1(×107 M−1)a | Kb2(×105 M−1)a | Kb1(×107 M−1)b | Kb2(×105 M−1)b | |
CQDP | 1.38 ± 0.56 | 1.02 ± 0.15 | 3.24 ± 1.21 | 3.26 ± 1.01 |
[Au(CQ)(PPh3)] PF6 | 3.79 ± 0.01 | 1.84 ± 0.89 | 5.27 ± 1.82 | 2.44 ± 1.69 |
Chloroquine diphosphate (CQDP), Chloroquine (CQ)
Averages of values calculated at 340 nm from absorption spectra.
Averages of values calculated at 389 nm from fluorescence spectra.