Table 1.
Mousea | Age | Anti-SRBCb | No. of PNA-hi B cells |
Total no. of nucleated spleen cells |
---|---|---|---|---|
(1)wildtype mouse1 |
11 weeks | 1/1024 | 195,428 | 72 × 106 |
(2) p53−/− mouse 1 |
11 weeks | 1/1024 | 205,616 | 74 × 106 |
(3) wildtype mouse2 |
16 weeks | 1/1024 | 251,645 | 84 × 106 |
(4) p53−/− mouse 2 |
16 weeks | 1/1024 | 270,228 | 226 × 106 |
(5) wildtype mouse 3 |
8 weeks | 1/2048 | 229,312 | 98 × 106 |
(6) p53−/− mouse 3 |
8 weeks | 1/2048 | 240,041 | 104 × 106 |
(7) ung control mouse |
8 weeks | 1/2048 | 265,482 | 84 × 106 |
(8) ung−/− mouse |
8 weeks | 1/2048 | 227,856 | 80 × 106 |
(9) p53+/− ung−/− mouse |
8 weeks | 1/1024 | 215,221 | 96 × 106 |
(10) p53−/− ung−/− mouse 1 |
8 weeks | 1/1024 | 220,662 | 89 × 106 |
(11) p53−/− ung−/− mouse 2 |
8 weeks | 1/1024 | 218,016 | 92 × 106 |
p21 wildtype mouse |
8 weeks | 1/1024 | ~185,000 | 90 × 106 |
p21−/− mouse |
8 weeks | 1/1024 | ~180,000 | 83 × 106 |
The numbers in parenthesis refer to the mouse numbers in Table 2A.
Hemaglutinin assay