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. Author manuscript; available in PMC: 2012 Mar 7.
Published in final edited form as: J Theor Biol. 2010 Dec 14;272(1):131–140. doi: 10.1016/j.jtbi.2010.11.042

Figure 3. Some important pathways (frequently observed at all methods and experimental conditions) on a simplified hepatic metabolic network.

Figure 3

Lactate enters P4 and P7 to produce glucose or to go into PPP. Similarly, glutamine is also used for glucose production (P470), aspartate (P358) or PPP (P12565). P43 shows the conversion of aspartate to urea. There are also pathways where conversion of lactate to cysteine and alanine (P41); and glutamine to glutamate (P21) take place. P2 includes arginine uptake, formation and secretion of ornithine and urea. P27933 are related to ketone bodies where conversion between acetoacetate and B-OH-butyrate by B-OH-butyrate dehydrogenise is seen. Note that external metabolites are given in bold boxes.