. Author manuscript; available in PMC: 2011 Sep 1.

Published in final edited form as: Gastroenterology. 2010 Jun 9;139(3):836–845.e1. doi: 10.1053/j.gastro.2010.06.009

Table 3.

ADRB2 allele frequency and Hardy-Weinberg Equilibrium (HWE) for single nucleotide polymorphisms across the ADRB2 locus.

Domain	RefSNP		Major allele freq (p)	Minor allele freq (q)	HWE
		N	Major allele freq (p)	Minor allele freq (q)	χ²	p
Promoter G-1023A	rs2053044	161	0.55	0.45	2.90	0.09
Promoter G-654A	none	162	0.65	0.35	0.20	0.65
Promoter C-468G	rs11168070	165	0.55	0.45	1.51	0.22
Promoter T-367C	rs11959427	166	0.55	0.45	2.48	0.12
Promoter T-47C	rs1042711	162	0.56	0.44	5.63	0.02
Gly16Arg, G265A	rs1042713	159	0.66	0.34	1.13	0.29
Glu27Gln, G298C	rs1042714	164	0.55	0.45	1.72	0.19
Leu84Leu, G252A	rs1042717	164	0.80	0.20	1.88	0.17
Arg175Arg, C523A	rs1042718	159	0.82	0.18	0.001	0.97

Footnote: Domains are numbered with respect to the translational start (AUG) codon. All ADRB2 SNPs except promoter T-47C fulfill the criteria of Hardy-Weinberg equilibrium. One member of each twinship was included in the analysis.