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. 2011 Jan 24;108(6):2605–2610. doi: 10.1073/pnas.1015788108

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Fig. 6. — Fluoxetine reduces TREK1 current and induces EGFP-Ct_TREK1 dissociation from the membrane. (A and C) Effect of fluoxetine application (100 μM) on TREK1 current and on the membrane fluorescence of EGFP-Ct_TREK1, respectively. (B and D) Effect of fluoxetine application (100 μM) on TREK1 current and on the membrane fluorescence of EGFP-Ct_TREK1 after 5HT2cR activation. (E) The histograms represent current inhibition induced by fluoxetine for TREK1 before and after 5HT2cR activation and for IRK1. (F) Relative fluorescence decrease induced by fluoxetine for TREK1 before and after 5HT2cR activation and for EFGP-PH_PLC and and EGFP-Ct_IRK1Q. Student's t test: ***P < 0.001. The numbers of cells tested are indicated in parentheses.