Table IV.

Parameter estimates from models in equations (8) and (14), EPIC-Norfolk study, n=323.

			Raw vitamin C intake				Calorie-adjusted vitamin C intake
			Unadjusted*		Covariate-adjusted†		Unadjusted*		Covariate-adjusted†
Parameter type	Parameter	Independent variable	Est.±s.e.	p-Value	Est.±s.e.	p-Value	Est.±s.e.	p-Value	Est.±s.e.	p-Value
Intercept	μT1	—	90.6±2.8	—	90.6±2.8	—	90.6±2.8	—	90.6±2.8	—
	μT2	—	94.8±2.8	—	94.8±2.8	—	94.6±2.9	—	94.6±2.9	—
	αq1	—	68.0±17.4	—	27.0±98.6	—	67.9±19.2	—	14.3±89.8	—
	αq2	—	66.5±18.2	—	20.3±100.9	—	66.2±20.0	—	8.2±91.9	—
	αm1	—	12.9±20.2	—	140.8±44.3	—	22.4±14.5	—	134.9±39.9	—
	αm2	—	17.9±21.2	—	150.5±45.4	—	28.0±15.1	—	145.3±40.9	—
Regression	βq	True vit. C intake	0.745±0.189	<0.001	0.721±0.167	<0.001	0.734±0.210	<0.001	0.716±0.181	<0.001
	βm	True vit. C intake	0.495±0.223	0.026	0.431±0.181	0.017	0.389±0.160	0.015	0.346±0.133	0.009
	γ̰q	Age (yrs)	—	—	0.99±0.84	0.24	—	—	0.81±0.77	0.29
		Male gender (1=yes/0=no)	—	—	−6.9±8.4	0.41	—	—	−8.0±7.6	0.29
		Height (cm)	—	—	−0.41±0.43	0.34	—	—	−0.25±0.39	0.52
		BMI (kg/m2)	—	—	1.67±0.70	0.018	—	—	1.68±0.64	0.009
		Current smoking	—	—	4.8±11.5	0.68	—	—	−0.6±10.5	0.95
		Past smoking	—	—	−2.8±5.6	0.61	—	—	−4.8±5.1	0.34
		Vitamin C supplement use	—	—	3.8±7.2	0.60	—	—	0.7±6.6	0.92
	γ̰m	Age (yrs)	—	—	−0.96±0.38	0.011	—	—	−1.01±0.34	0.003
		Male gender (1=yes/0=no)	—	—	−8.9±3.8	0.018	—	—	−10.8±3.4	0.002
		Height (cm)	—	—	−0.22±0.19	0.25	—	—	−0.10±0.17	0.56
		BMI (kg/m2)	—	—	−0.74±0.31	0.019	—	—	−0.81±0.28	0.005
		Current smoking	—	—	−8.3±5.1	0.11	—	—	−10.4±4.6	0.025
		Past smoking	—	—	0.7±2.5	0.77	—	—	0.6±2.3	0.78
		Vitamin C supplement use	—	—	14.1±3.3	<0.001	—	—	13.9±2.9	<0.001
Variance component	${\sigma }_S^2$	—	647±301	—	700±309	—	783±318	—	834±331	—
	${\sigma }_D^2$	—	822±429	—	736±351	—	1168±570	—	1032±462	—
	${\sigma }_T^2$	—	853±369	—	884±356	—	1076±427	—	1092±404	—
	${\sigma }_q^2$	—	1848±428	—	1718±380	—	1652±387	—	1486±332	—
	${\sigma }_r^2$	—	1127±454	—	998±431	—	1045±453	—	904±424	—
	${\sigma }_m^2$	—	154±123	—	77±88	—	188±90	—	104±66	—
	${\sigma }_{\mathit{\text{eq}}}^2$	—	1313±226	—	1348±214	—	967±216	—	1023±185	—
	${\sigma }_{\mathit{\text{er}}}^2$	—	571±230	—	610±193	—	480±286	—	546±235	—
	${\sigma }_{\mathit{\text{em}}}^2$	—	129±73	—	160±50	—	141±64	—	166±45	—
Correlation	ρqr	—	0.61±0.10	—	0.62±0.10	—	0.62±0.12	—	0.61±0.11	—
	ρT	—	0.52±0.20	—	0.58±0.17	—	0.46±0.23	—	0.53±0.20	—
Deattenuation	λRQ	—	0.404±0.041	—	0.403±0.041	—	0.472±0.043	—	0.471±0.044	—
factor			(0.324, 0.484)‡		(0.322, 0.483)‡		(0.388, 0.556)‡		(0.385, 0.556)‡
	λTQ	—	0.175±0.077	—	0.181±0.075	—	0.247±0.095	—	0.255±0.094	—
			(0.073,0.416)§		(0.081, 0.406)§		(0.116, 0.526)§		(0.124, 0.525)§

^*Based on Equation (8).

^†Based on Equation (14) after adjusting for the covariates in Table II.

^‡95 per cent CI for λ_RQ.

^§95 per cent CI for λ_TQ based on equation (12).