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. 2011 Feb 14;6(2):e16623. doi: 10.1371/journal.pone.0016623

Table 2. Clinical, biological features and karyotype of the p-AML patients.

Patients Age1/ FAB Karyotype FISH Allograft Survival
Sex duration >
12 months
p-1 68/F M1 45,XX,−7 ND No info No info
p-2 34/M M6 45,XY,−7 ND no no info
p-3 66/M M1 48,XY,+8,+13 ND No Yes
p-4 54/F M5 47,XX,+i(21q) ND Yes Yes
p-5 32/M M5 47,XY,t(2;14)(q21;q32),+4 wcp2, wcp14 No No
p-6 44/F M5 46,XX,der(5)t(1;5)(q32;q35),inv(9)(p12q13)[20]. MLL WT, wcp1, No No info
ish(5p15,5q31)×2,add(5)(q35?)(wcp1+) wcp5,wcp17
p-7 68/M M5 46,XY,del(7)(q21q31),der(9)(WPC9+),?der(11)(q23)/46,XY[2] MLL WT No No
p-8 25/F M3 46,XX,t(15;17)(q22;q21) PML-RARA fus
p-9 46/F M3 46,XX,t(15;17)(q22;q21) PML RARA fus No No info
p-10 46/F M3 46,XX,t(15;17)(q22;q21) PML RARA fus No Yes
p-11 27/M M3 46,XY,i(3)(p10),i(3q),t(15;17)(q22;q21) PML RARA fus No Yes
p-12 47/M M3 46,XY,t(15;17)(q22;q21) PML RARA fus No No
p-13 73/M M3 46,XY,t(15;17)(q22;q21) PML RARA fus No Yes
p-14 35/M M3 46,XY,t(15;17)(q22;q21) PML RARA fus No Yes
p-15 57/M M3 46,XY,t(15;17)(q22;q21) PML RARA fus No Yes
p-16 54/M M4 46,XY,t(16;16)(p13;q22) CBFB sep Yes No
p-17 26/M M4Eo 46,XY,t(16;16)(p13;q22) ND Yes Yes
p-18 19/M M2 45,XY,t(8;21)(q22;q22),del(9)(q31q34) ND No Yes
p-19 37/M M1 45,XY,t(9;11)(p22;q23),del(7)(p12;p21) MLL sep No Yes
p-20 25/M M1 46,XY,t(9;11)(p22;q23) MLL sep Yes Yes
p-21 80/M M1 46,XY[3]/50–53,XY,−1,−3,−4,−15?,−21,+7 to 10 mar ND No No
p-22 42/M M1 46,XY,t(3;5)(q25;q34),del(4)(q26),der(12)t(4;12) WCP(3; 4) Yes Yes
(q28?;p12),der(18)t(12;18)(p12;q21),mar? WCP(5; 12)
p-23 30/M M5 46,XY,t(11;12)(q13;p13)[2]46,XY,id,der(1)t(1;1) ND No No
(p16;q12)[1]/46,XY,id,der(7)t(1;7)(q12;q36)[1]/
46,XY,id,der(9)t(1;9)(q12;p24)[2]46,XY,id,der(14)
t(1;14)(q12;p10)[2]46,XY,id,der(20)t(1;20)(q12;p12)
[1]46,XY,id,der(20)t(1;20)(q12;q13)[2]46,XY,id,
der(21)t(1;21)(q12;q10)[3]
p-24 71/M M2 43–46,XY,−2,−5,−7,−16,+mar1,+mar2,+mar3, +mar4, ND No No
variations
p-25 63/F M2 46,XX ND No Yes
p-26 52/F M2 46,XX MLL WT Yes Yes
p-27 23/F M2 46,XX MLL WT No Yes
p-28 23/F M5 46,XX MLL WT Yes Yes
p-29 45/F M5 46,XX ND No No
p-30 73/F M5 46,XX ND No No
p-31 31/M M0 46,XY MLL WT No No info
p-32 75/M M1 46,XY MLL WT No No
p-33 41/M M1 46,XY MLL WT Yes No info
p-34 48/M M2 46,XY MLL WT Yes Yes
p-35 38/M M2 46,XY MLL WT No No
p-36 63/M M4 46,XY ND No No

1 = age at diagnosis of AML. FAB column: FAB classification. FISH column: MLL WT = MLL Wild Type; MLL sep = MLL rearranged (separated); PML-RARA fus = fusion of PML and RARA gene; WCP = whole chromosome paint; ND = Not Done.