Table 2. Clinical, biological features and karyotype of the p-AML patients.
Patients | Age1/ | FAB | Karyotype | FISH | Allograft | Survival |
Sex | duration > | |||||
12 months | ||||||
p-1 | 68/F | M1 | 45,XX,−7 | ND | No info | No info |
p-2 | 34/M | M6 | 45,XY,−7 | ND | no | no info |
p-3 | 66/M | M1 | 48,XY,+8,+13 | ND | No | Yes |
p-4 | 54/F | M5 | 47,XX,+i(21q) | ND | Yes | Yes |
p-5 | 32/M | M5 | 47,XY,t(2;14)(q21;q32),+4 | wcp2, wcp14 | No | No |
p-6 | 44/F | M5 | 46,XX,der(5)t(1;5)(q32;q35),inv(9)(p12q13)[20]. | MLL WT, wcp1, | No | No info |
ish(5p15,5q31)×2,add(5)(q35?)(wcp1+) | wcp5,wcp17 | |||||
p-7 | 68/M | M5 | 46,XY,del(7)(q21q31),der(9)(WPC9+),?der(11)(q23)/46,XY[2] | MLL WT | No | No |
p-8 | 25/F | M3 | 46,XX,t(15;17)(q22;q21) | PML-RARA fus | ||
p-9 | 46/F | M3 | 46,XX,t(15;17)(q22;q21) | PML RARA fus | No | No info |
p-10 | 46/F | M3 | 46,XX,t(15;17)(q22;q21) | PML RARA fus | No | Yes |
p-11 | 27/M | M3 | 46,XY,i(3)(p10),i(3q),t(15;17)(q22;q21) | PML RARA fus | No | Yes |
p-12 | 47/M | M3 | 46,XY,t(15;17)(q22;q21) | PML RARA fus | No | No |
p-13 | 73/M | M3 | 46,XY,t(15;17)(q22;q21) | PML RARA fus | No | Yes |
p-14 | 35/M | M3 | 46,XY,t(15;17)(q22;q21) | PML RARA fus | No | Yes |
p-15 | 57/M | M3 | 46,XY,t(15;17)(q22;q21) | PML RARA fus | No | Yes |
p-16 | 54/M | M4 | 46,XY,t(16;16)(p13;q22) | CBFB sep | Yes | No |
p-17 | 26/M | M4Eo | 46,XY,t(16;16)(p13;q22) | ND | Yes | Yes |
p-18 | 19/M | M2 | 45,XY,t(8;21)(q22;q22),del(9)(q31q34) | ND | No | Yes |
p-19 | 37/M | M1 | 45,XY,t(9;11)(p22;q23),del(7)(p12;p21) | MLL sep | No | Yes |
p-20 | 25/M | M1 | 46,XY,t(9;11)(p22;q23) | MLL sep | Yes | Yes |
p-21 | 80/M | M1 | 46,XY[3]/50–53,XY,−1,−3,−4,−15?,−21,+7 to 10 mar | ND | No | No |
p-22 | 42/M | M1 | 46,XY,t(3;5)(q25;q34),del(4)(q26),der(12)t(4;12) | WCP(3; 4) | Yes | Yes |
(q28?;p12),der(18)t(12;18)(p12;q21),mar? | WCP(5; 12) | |||||
p-23 | 30/M | M5 | 46,XY,t(11;12)(q13;p13)[2]46,XY,id,der(1)t(1;1) | ND | No | No |
(p16;q12)[1]/46,XY,id,der(7)t(1;7)(q12;q36)[1]/ | ||||||
46,XY,id,der(9)t(1;9)(q12;p24)[2]46,XY,id,der(14) | ||||||
t(1;14)(q12;p10)[2]46,XY,id,der(20)t(1;20)(q12;p12) | ||||||
[1]46,XY,id,der(20)t(1;20)(q12;q13)[2]46,XY,id, | ||||||
der(21)t(1;21)(q12;q10)[3] | ||||||
p-24 | 71/M | M2 | 43–46,XY,−2,−5,−7,−16,+mar1,+mar2,+mar3, +mar4, | ND | No | No |
variations | ||||||
p-25 | 63/F | M2 | 46,XX | ND | No | Yes |
p-26 | 52/F | M2 | 46,XX | MLL WT | Yes | Yes |
p-27 | 23/F | M2 | 46,XX | MLL WT | No | Yes |
p-28 | 23/F | M5 | 46,XX | MLL WT | Yes | Yes |
p-29 | 45/F | M5 | 46,XX | ND | No | No |
p-30 | 73/F | M5 | 46,XX | ND | No | No |
p-31 | 31/M | M0 | 46,XY | MLL WT | No | No info |
p-32 | 75/M | M1 | 46,XY | MLL WT | No | No |
p-33 | 41/M | M1 | 46,XY | MLL WT | Yes | No info |
p-34 | 48/M | M2 | 46,XY | MLL WT | Yes | Yes |
p-35 | 38/M | M2 | 46,XY | MLL WT | No | No |
p-36 | 63/M | M4 | 46,XY | ND | No | No |
1 = age at diagnosis of AML. FAB column: FAB classification. FISH column: MLL WT = MLL Wild Type; MLL sep = MLL rearranged (separated); PML-RARA fus = fusion of PML and RARA gene; WCP = whole chromosome paint; ND = Not Done.